Objective: According to WHO, snake bite is one of the most important Neglected Tropical Diseases (NTD) (in 2017 again) in terms of both incidence, severity and high mortality, challenges being the shortage and affordability of anti-venom. We reported two cases of patients complaining of pain and swelling due to snake bite.
Discussion: Snake venoms stimulate the activation of mast cells which lead to histamine release, inducing vascular permeability and vasodilatation leading to extravasation. In the present cases, the patients presented with local pain and swelling. Disseminated Intravascular Coagulation (DIC) was observed along with Acute Kidney Injury (AKI).
Conclusions: Extracorporeal cytokine adsorption device along with standard of care seems to be a promising and safe treatment modality to stabilize and recover snake bite envenomation induced complications leading to shorter ICU stays and better survival.